Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp320 | Osteoporosis: treatment | ECTS2014

Effects of preventive long-term treatment with strontium ranelate and zoledronic acid to ovariectomized rats on bone microstructure

Martin-Fernandez Marta , Gomez-Chinchon Marina , Guede David , Caeiro Jose Ramon , Diaz-Curiel Manuel , De la Piedra Concepcion

Many pharmacological treatments have been developed in order to prevent or treat postmenopausal osteoporosis. There is not any study in the literature comparing long-term treatments of osteoporosis. The aim of this work was to studythe effects of long-term prevention treatment with zoledronic acid (ZA) and strontium ranelate (SrR) on bone microstructure in ovariectomized rats.Sixty 6-month-old female Wistar rats were used in this study and divided into f...